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Physico chemistry of solids, thin films, biotechnologies
Applications for micro & nano- technologies, energy, health ...

> Research > IMBM

Drug Delivery


Our aim is to engineer layer-by-layer films for the delivery of bioactive molecules, including chemokines, hydrophobic drugs and peptides. We aim to understand how breast cancer cells respond to these biofunctional films and the molecular events underlying the cell response.

Group Members

       Arunkumar Rengaraj (Post-doc)
[legende-image]1383921700868[/legende-image]   Paul Machillot (Assistant Engineer)
       Marianne Weidenhaupt (MCU)

Selected Publications

[legende-image]1383921700437[/legende-image]The effect of delivering the chemokine SDF-1? in a matrix-bound manner on myogenesis.
Dalonneau F, Liu XQ, Rabir R, Almodovar J, Mertani HC, Bruckert C, Mertani H, Albiges-Rizo C, Weidenhaupt M, Lortat-Jacob H, Picart C.
Biomaterials. 2014.
[legende-image]1383921700441[/legende-image]Asymmetric free-standing film with multifunctional anti-bacterial and self-cleaning properties.
Shen L, Wang B, Wang J, Fu J, Picart C, Ji J.
ACS Appl. Mater. Interfaces. 2012.
[legende-image]1383921700438[/legende-image]Polyelectrolyte multilayer nanoshells with hydrophobic nanodomains for the delivery of Paclitaxel.
Boudou T, Kharkar P, Jing J, Guillot R, Pignot-Paintrand I, Auzely-Velty R, Picart C.
J. Control. Release. 2012.
[legende-image]1383921700439[/legende-image]Hydrophobic shell loading of biopolyelectrolyte capsules.
Cui D, Jing J, Boudou T, Pignot-Paintraind I, De Koker S, De Geest BG, Picart C, Auzély-Velty R.
Adv. Mater. 2011. 
[legende-image]1383921700440[/legende-image]Contact-killing polyelectrolyte microcapsules based on chitosan derivatives.
Cui D, Anna Szarpak A, Pignot-Paintrand I, Varrot A, Boudou T, Detrembleur C,
Jérôme C, Picart C, Auzély-Velty R.
Adv. Funct. Mat. 2010.

Date of update April 8, 2018

Univ. Grenoble Alpes