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Synthèse et propriétés de monocristaux, de poudres, films minces ou hétérostructures

Etudes à l'interface avec la matière biologique

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LMGP seminar - Didier LETOURNEUR

Publié le 30 octobre 2012
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Conférence du 29 novembre 2012 au 30 novembre 2012
à 10h30 - Conference room, 2nd floor LMGP
LMGP / Grenoble INP Minatec
3 parvis Louis Néel - Grenoble
Didier LETOURNEUR,
DR INSERM, INSERM U698-CHU Bichat PARIS, Cardiovascular Bioengineering

Three-dimensional Scaffolds for Cardiovascular Tissue Engineering

Abstract
One main challenge of tissue engineering is to create an optimal environment for growing therapeutic cells to regenerate damaged tissues. This environment can be reconstituted by using 3D matrices, in which cells can be organized into a tissue-like structure. We have prepared pullulan/dextran porous matrices having controlled pores and porosity that allowed the proliferation and survival of various stem cells. These porous hydrogels have architectural characteristics adapted to the culture in 3D. Further studies have demonstrated the performance of these matrices for tissue regeneration. Examples for heart, skin and bone will be presented.
Applications of these scaffolds included the 3D cell culture, the tissue integration/regeneration, and the design of biocompatible materials for cell, drug and gene delivery by chemical functionalization of the polymers and new formulations.

 

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mise à jour le 14 novembre 2012

  • Tutelle CNRS
  • Tutelle Grenoble INP
Univ. Grenoble Alpes