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Synthèse et propriétés de monocristaux, de poudres, films minces ou hétérostructures

Etudes à l'interface avec la matière biologique
PUBLICATIONS:


2014
27. Ramade A, Legant WR, Picart C, Chen CS, and Boudou T. Microfabrication of a platform to measure and manipulate the mechanics of engineered microtissues. Methods Cell Biol 121: 191–211, 2014

26. Wang H, Svoronos AA, Boudou T, Sakar MS, Schell JY, Morgan JR, Chen CS, Shenoy VB. Necking and failure of constrained 3D microtissues induced by cellular tension. PNAS 110: 20923-20928. 2014


2013


25. Monge C, Saha N, Boudou T, Pózos-Vásquez C, Dulong V, Glinel K, Picart C. Rigidity-patterned polyelectrolyte films to control myoblast cell adhesion and spatial organization. Adv. Funct. Mater. 23: 3432-3442, 2013

24. Caridade SG, Monge C, Gilde FD, Boudou T, Mano JF, Picart C. Free-standing polyelectrolyte membranes made of chitosan and alginate. Biomacromolecules 14: 1653-1660, 2013

23. Almodovar J, Crouzier T, Selimovic S, Boudou T, Khademhosseini A, Picart C. Gradients of physical and biochemical cues on polyelectrolyte multilayer films generated via microfluidics. Lab on a Chip 13:1562-1570, 2013

22. Zhao R, Boudou T, Wang W-G, Chen CS, Reich DH. Decoupling cell and matrix mechanics in engineered microtissues using magnetically actuated microcantilevers.Adv. Mater. 25:1699-1705, 2013

21. West AR, Zaman N, Cole DJ, Walker MJ, Legant WR, Boudou T, Chen CS, Favreau JT, Gaudette GR, Cowley EA, Maksym GN. Development and characterisation of a 3D multi-cell microtissue culture model of airway smooth muscle. AJP Lung Cell. Mol. Physiol. 304:L4-16, 2013


2012

20. Sakar MS, Neal D, Boudou T, Borochin MA, Li Y, Weiss R, Kamm RD, Chen CS, Asada HH. Formation and optogenetic control of engineered 3D skeletal muscle bioactuators. Lab Chip 12: 4976-4985, 2012

19. Boudou T, Kharkar P, Jing J, Guillot R, Pignot-Paintrand I, Auzely-Velty R, Picart C. Polyelectrolyte multilayer nanoshells with hydrophobic nanodomains for delivery of Paclitaxel. J. Controlled Release 159: 403-412, 2012

18. Boudou T, Legant WR, Mu A, Borochin MA, Thavandiran N, Radisic M, Zandstra PW, Epstein JA, Margulies KB, Chen CS. A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Eng. A 18: 910-919, 2012


2011

17. Eyckmans J, Boudou T, Yu X, Chen CS. A hitchhiker's guide to mechanobiology. Dev. Cell. 21: 35-47, 2011

16. Yamanlar S, Sant S, Boudou T, Picart C and Khademhosseini A. Surface functionalization of hyaluronic acid hydrogels by polyelectrolyte multilayer films. Biomaterials 32: 5590-99, 2011

15. Cui D, Jing J, Boudou T, Pignot-Paintrand I, De Koker S, De Geest BG, Picart C, Auzély-Velty R. Hydrophobic shell loading of biopolyelectrolyte capsules. Adv. Mater. 23: H200-4, 2011

14. Crouzier T, Fourel L, Boudou T, Albigès-Rizo C and Picart C. Presentation of BMP-2 from a soft biopolymeric film unveils its activity on cell adhesion and migration. Adv. Mat. 23: H111-8, 2011

13. Boudou T, Crouzier T, Nicolas C, Picart C. Boudou T, Crouzier T, Nicolas C, Ren K, Picart C. Polyelectrolyte multilayer nanofilms used as thin materials for cell mechano-sensitivity studies. Macromol. Biosci. 11: 77-89, 2011


2010

12. Crouzier T, Boudou T, Picart C. Polysaccharide-based polyelectrolyte multilayers. Curr. Opin. Colloid Interface Sci. 15: 417-426, 2010

11. Cui D, Szarpak A, Pignot-Paintrand I, Varrot A, Boudou T, Detrembleur C, Jerôme C, Picart C, Auzély-Velty R. Contact-killing polyelectrolyte microcapsules based on chitosan derivatives. Adv. Funct. Mat. 20: 3303-3312, 2010

10. Crouzier T, Szarpak A, Boudou T, Auzely-Velty R, Picart C. Polysaccharide blend multilayers containing hyaluronan and heparin as a delivery system for rhBMP-2. Small 6: 651-662, 2010

9. Boudou T, Crouzier C, Ren K, Blin G, Picart C. Multiple functionalities of polyelectrolyte multilayer films: New biomedical applications. Adv. Mater. 22: 441-467, 2010


2009

8. Kadi S, Cui D, Bayma E, Boudou T, Nicolas C, Glinel K, Picart C, Auzly-Velty R. Alkylamino hydrazide derivatives of hyaluronic acid: Synthesis, characterization in semidilute aqueous solutions, and assembly into thin multilayer films. Biomacromolecules 10: 2875-84, 2009

7. Pozos-Vázquez C, Boudou T, Dulong V, Nicolas C, Picart C, Glinel K. Variation of polyelectrolyte film stiffness by photo-cross-linking: A new way to control cell adhesion. Langmuir 25: 3556-63, 2009

6. Boudou T, Crouzier C, Auzély-Velty R, Glinel K, Picart C. Internal composition versus the mechanical properties of polyelectrolyte multilayer films: the influence of chemical cross-linking. Langmuir 25: 13809-19, 2009

5. Schiavone P, Chassat F, Boudou T, Promayon E, Valdivia F, Payan Y. In vivo measurement of human brain elasticity using a light aspiration device. Med. Image Anal. 13: 673-8, 2009

4. Boudou T, Ohayon J, Picart C, Pettigrew RI, Tracqui P. Nonlinear elastic properties of polyacrylamide gels: implications for quantification of cellular forces. Biorheology 46: 191-205, 2009


2008

3. Tracqui P, Ohayon J, Boudou T. Theoretical analysis of the adaptative contractile behaviour of a single cardiomyocyte cultured on elastic substrates with varying stiffness. J. Theor. Biol. 255: 92-105, 2008


2006

2. Boudou T, Ohayon J, Picart C, Tracqui P. An extended relationship for the characterization of Young's modulus and Poisson's ratio of tunable polyacrylamide gels. Biorheology 43: 721-8, 2006

1. Boudou T, Ohayon J, Arntz Y, Finet G, Picart C, Tracqui P. An extended modeling of the micropipette aspiration experiment for the characterization of the Young's modulus and Poisson's ratio of adherent thin biological samples: Numerical and experimental studies. J. Biomech. 39: 1677-85, 2006

 

Date of update February 21, 2014


Taxol-loaded microcapsules on a breast cancer cell (MDA-MB 231)




C2C12 myoblasts aligned on rigidity lines




C2C12 myoblasts spreding on PEM films


FE Modeling of cardiomyocyte contraction




Brain pipette aspiration experiment


A 600µm microtissue made of collagen and fibroblasts




FE modeling of micropipette aspiration
  • Tutelle CNRS
  • Tutelle Grenoble INP
Univ. Grenoble Alpes