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Synthèse et propriétés de monocristaux, de poudres, films minces ou hétérostructures

Etudes à l'interface avec la matière biologique

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Publication de Charlotte Vendrely 2017

Publié le 11 septembre 2017
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Communiqué 21 juillet 2017

Le papier "A synthetic redox biofilm made from metalloprotein–prion domain chimera nanowires" a été publié dans Nature Chemistry

Ici vous trouverez le papier de Charlotte Vendrely

"Engineering bioelectronic components and set-ups that mimic natural systems is extremely challenging. Here we report the design of a protein-only redox film inspired by the architecture of bacterial electroactive biofilms. The nanowire scaffold is formed using a chimeric protein that results from the attachment of a prion domain to a rubredoxin (Rd) that acts as an electron carrier. The prion domain self-assembles into stable fibres and provides a suitable arrangement of redox metal centres in Rd to permit electron transport. This results in highly organized films, able to transport electrons over several micrometres through a network of bionanowires. We demonstrate that our bionanowires can be used as electron-transfer mediators to build a bioelectrode for the electrocatalytic oxygen reduction by laccase. This approach opens opportunities for the engineering of protein-only electron mediators (with tunable redox potentials and optimized interactions with enzymes) and applications in the field of protein-only bioelectrodes."

 



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mise à jour le 11 septembre 2017

  • Tutelle CNRS
  • Tutelle Grenoble INP
Univ. Grenoble Alpes