We develop 2D platforms able to mimic defined aspects of the extracellular matrix, for molecular and cellular studies.Surfaces functionalization with glycans, adhesion peptides, growth factors and chemokines is precisely controlled in terms of molecular surface density and orientation. These well-defined platforms can be used for cellular studies: differentiation, migration, signaling, and molecular cross-talks (more info).
We develop biomaterials for investigating the signaling mechanisms of Bone Morphogenetic Proteins (BMP) presented in a "matrix-bound" manner as well as for enhancing osteoinductive properties of BMP-loaded films onto implants for orthopedic, dental and maxillo-facial surgery, to enhance their osteoinductive properties (more info).
We engineer biopolymeric films and capsules for the delivery of bioactive molecules, including chemokines, hydrophobic drugs or peptides, and to study the response of breast cancer cells to these biofunctional films (more info).
Written by Thomas Boudou
Date of update November 3, 2017
Recherche Interfaces entre Matériaux et Matière Biologique (IMBM)